Description

Gives an estimation of the sequencing bias based on known invariant sites

Input

name:type
description
pattern

meta:map

Groovy Map containing sample information e.g. [ id:‘test’, single_end:false ]

bam:file

BAM file

*.bam

bai:file

BAI file

*.bai

empiric:file

Optional txt file from PMD estimations (atlas/pmd)

*.txt

readgroups:file

read groups

alleles:file

Optional bed file with known alleles

*.bed

invariant_sites:file

Optional bed file with invariant site coordinates

*.bed

Output

name:type
description
pattern

recal_patterns

meta:map

Groovy Map containing sample information e.g. [ id:‘test’, single_end:false ]

*.txt:file

file containing the sequencing bias for each of the Read Group pools

*.txt

versions

versions.yml:file

File containing software versions

versions.yml

Tools

atlas
GPL v3

ATLAS, a suite of methods to accurately genotype and estimate genetic diversity