Description

Condenses homRef blocks in a single-sample GVCF

Input

name:type
description
pattern

meta:map

Groovy Map containing sample information e.g. [ id:‘test’, single_end:false ]

gvcf:file

GVCF file created using HaplotypeCaller using the ‘-ERC GVCF’ or ‘-ERC BP_RESOLUTION’ mode

*.{vcf,gvcf}.gz

tbi:file

Index of the GVCF file

*.tbi

intervals:file

Bed file with the genomic regions included in the library (optional)

fasta:file

The reference fasta file

*.fasta

fai:file

Index of reference fasta file

fasta.fai

dict:file

GATK sequence dictionary

*.dict

dbsnp:file

VCF file containing known sites (optional)

dbsnp_tbi:file

VCF index of dbsnp (optional)

Output

name:type
description
pattern

vcf

meta:map

Groovy Map containing sample information e.g. [ id:‘test’, single_end:false ]

*.rb.g.vcf.gz:file

The reblocked GVCF file

*.rb.g.vcf.gz

*.tbi:file

Index of the reblocked GVCF file

*.tbi

versions

versions.yml:file

File containing software versions

versions.yml

Tools

gatk4
Apache-2.0

Developed in the Data Sciences Platform at the Broad Institute, the toolkit offers a wide variety of tools with a primary focus on variant discovery and genotyping. Its powerful processing engine and high-performance computing features make it capable of taking on projects of any size.

gatk.broadinstitute.org/hc/en-us gatk.broadinstitute.org/hc/en-us/categories/360002369672s 10.1158/1538-7445.AM2017-3590
Github user nvnieuwk
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