Description

Defines chunks where to run imputation

Input

Name (Type)
Description
Pattern

meta (map)

Groovy Map containing sample information
e.g. [ id:‘test’, single_end

]

input (file)

Target dataset in VCF/BCF format defined at all variable positions.
The file could possibly be without GT field (for efficiency reasons a file containing only the positions is recommended).

*.{vcf,bcf,vcf.gz,bcf.gz}

input_index (file)

Index file of the input VCF/BCF file containing genotype likelihoods.

*.{vcf.gz.csi,bcf.gz.csi}

region (string)

Target region, usually a full chromosome (e.g. chr20:1000000-2000000 or chr20).
For chrX, please treat PAR and non-PAR regions as different choromosome in order to avoid mixing ploidy.

map (file)

File containing the genetic map.

*.gmap

model (string)

Algorithm model to use:
“recursive”: Recursive algorithm
“sequential”: Sequential algorithm (Recommended)
“uniform-number-variants”: Experimental. Uniform the number of variants in the sequential algorithm

{recursive,sequential,uniform-number-variants}

Output

Name (Type)
Description
Pattern

meta (map)

Groovy Map containing sample information
e.g. [ id:‘test’, single_end

]

versions (file)

File containing software versions

versions.yml

txt (file)

Tab delimited output txt file containing buffer and imputation regions.

*.{txt}

Tools

glimpse2
MIT

GLIMPSE2 is a phasing and imputation method for large-scale low-coverage sequencing studies.