maximum-likelihood analysis of gene essentialities computation
meta{:bash}
:map
Groovy Map containing sample information e.g. [ id:‘test’, single_end:false ]
count_table{:bash}
:file
Count table file. Each line in the table should include sgRNA name (1st column), target gene (2nd column) and read counts in each sample.
*.{txt,tsv}
design_matrix{:bash}
Design matrix describing the samples and conditions
gene_summary{:bash}
*.gene_summary.txt{:bash}
Gene summary file describing the fitness score and associated p-values.
*.{gene_summary}
sgrna_summary{:bash}
*.sgrna_summary.txt{:bash}
sgRNA summary file describing the sgRNA and associated gene
versions{:bash}
versions.yml{:bash}
File containing software versions
versions.yml
MAGeCK (Model-based Analysis of Genome-wide CRISPR-Cas9 Knockout), an algorithm to process, QC, analyze and visualize CRISPR screening data.