Description

Evaluate microsattelite instability (MSI) using paired tumor-normal sequencing data

Input

name:type
description
pattern

meta

:map

Groovy Map containing sample information e.g. [ id:‘test’, single_end:false ]

normal_bam

:file

Coordinate sorted BAM/CRAM/SAM file from normal tissue

*.{bam,cram,sam}

normal_bai

:file

Index for coordinate sorted BAM/CRAM/SAM file from normal tissue

*.{bam,cram,sam}

tumor_bam

:file

Coordinate sorted BAM/CRAM/SAM file from tumor tissue

*.{bam,cram,sam}

tumor_bai

:file

Index for coordinate sorted BAM/CRAM/SAM file from tumor tissue

*.{bam,cram,sam}

metascan

:file

metascan file

homopolymers

:file

Output file from MSIsensor scan module

*.msisensor_scan.tab

Output

name:type
description
pattern

output

meta

:map

Groovy Map containing sample information e.g. [ id:‘test’, single_end:false ]

${prefix}

:file

Output file from MSIsensor msi module

output_dis

meta

:map

Groovy Map containing sample information e.g. [ id:‘test’, single_end:false ]

${prefix}_dis

:file

Output file from MSIsensor module

output_germline

meta

:map

Groovy Map containing sample information e.g. [ id:‘test’, single_end:false ]

${prefix}_germline

:file

Output file from MSIsensor module

output_somatic

meta

:map

Groovy Map containing sample information e.g. [ id:‘test’, single_end:false ]

${prefix}_somatic

:file

Output file from MSIsensor module

versions_msisensor

${task.process}

:string

The name of the process

msisensor

:string

The name of the tool

msisensor 2>&1 | sed -nE 's/Version:\sv([0-9]\.[0-9])/\1/ p'

:string

The expression to obtain the version of the tool

Topics

name:type
description
pattern

versions

${task.process}

:string

The name of the process

msisensor

:string

The name of the tool

msisensor 2>&1 | sed -nE 's/Version:\sv([0-9]\.[0-9])/\1/ p'

:string

The expression to obtain the version of the tool

Tools

msisensor
MIT

MSIsensor is a C++ program to detect replication slippage variants at microsatellite regions, and differentiate them as somatic or germline.