Description

Genotype structural variants using paragraph and grmpy

Input

Name (Type)
Description
Pattern

meta (map)

Groovy Map containing sample information
e.g. [ id:‘test’, single_end

]

variants (file)

A VCF or JSON file containing called structural variants

*.{vcf,json}

variants_index (file)

The index for the VCF file

*.tbi

reads (file)

BAM or CRAM file(s) to genotype against. These should be specified inside the manifest

*.{bam,cram}

reads_index (file)

The index/indices for the BAM/CRAM file(s)

*.{bai,crai}

manifest (file)

A tab separated file containing information on the BAM/CRAM files.
This information can be generated using paragraph/idxdepth.
More information can be found here: https://github.com/Illumina/paragraph#sample-manifest

meta2 (map)

Groovy Map containing sample information for the FASTA file
e.g. [ id:‘test’, single_end

]

fasta (file)

The reference FASTA file used to generate the VCF and BAM/CRAM files

*.{fa,fasta,fna}

meta3 (map)

Groovy Map containing sample information for the FASTA index file
e.g. [ id:‘test’, single_end

]

fasta_fai (file)

The index of the reference FASTA file

*.fai

Output

Name (Type)
Description
Pattern

meta (map)

Groovy Map containing sample information
e.g. [ id:‘test’, single_end

]

versions (file)

File containing software versions

versions.yml

vcf (file)

The genotyped VCF file in BGZIP format

*.vcf.gz

json (file)

The genotyped JSON file in GZIP format

*.json.gz

Tools

paragraph
Apache License 2.0

Graph realignment tools for structural variants