nf-core/tumourevo
Analysis pipleine to model tumour clonal evolution from WGS data (driver annotation, quality control of copy number calls, subclonal and mutational signature deconvolution)
22.10.6
.
Learn more.
Define where the pipeline should find input data and save output data.
Path to comma-separated file containing information about the samples in the experiment.
string
^\S+\.csv$
You will need to create a design file with information about the samples in your experiment before running the pipeline. Use this parameter to specify its location. It has to be a comma-separated file with 3 columns, and a header row.
The output directory where the results will be saved. You have to use absolute paths to storage on Cloud infrastructure.
string
Path to reference fast file.
string
Reference genome name.
string
List of tools for running the pipeline.
string
mobster,viber,pyclone-vi,sparsesignatures,sigprofiler
Method used to save pipeline results to output directory.
string
copy
Flag for filtering QC mutations or not.
string
string
Path to VEP cache.
string
VEP cache version.
string
VEP species.
string
VEP reference genome name.
string
Add an extra custom argument to VEP.
string
--everything --filter_common --per_gene --total_length --offline --format vcf
Path to driver table.
string
https://raw.githubusercontent.com/nicola-calonaci/test-datasets/evoverse/data/DRIVER_ANNOTATION/DNDSCV/RefCDS_human_GRCh38_GencodeV18_recommended.rda
Flag for filtering mutations from vcf.
string
TRUE
string
c(\'1:0\', \'1:1\', \'2:0\', \'2:1\', \'2:2\')
integer
integer
100
number
0.005
string
NULL
number
0.05
number
0.015
integer
1
string
rightmost
string
TRUE
string
1:1
string
absolute
integer
25
number
0.1
string
FALSE
string
ENTROPY
integer
1
string
FALSE
string
TRUE
string
beta-binomial
integer
100
integer
100
integer
20
string
1:5
string
peaks
integer
5
string
c(TRUE,FALSE)
number
1e-10
integer
250
string
MM
integer
12345
string
reICL
string
FALSE
string
TRUE
number
0.02
integer
10
string
FALSE
string
NULL
integer
10
integer
10
number
0.000001
integer
1
integer
1
integer
5000
number
1e-10
string
prior
string
FALSE
number
0.05
number
0.02
string
FALSE
integer
1
integer
10000
integer
5000
integer
100
string
2:10
string
NULL
string
NULL
string
TRUE
integer
30
integer
10
integer
10000
string
all
number
0.01
integer
50
integer
5
string
c(0.01, 0.05, 0.1, 0.2)
integer
string
TRUE
integer
12345
string
c(0.00, 0.01, 0.05, 0.10)
Mode of publishing the SigProfiler genome.
string
move
boolean
true
string
boolean
string
matrix
integer
1
integer
25
string
96,DINUC,ID
integer
100
boolean
true
string
gmm
string
random
integer
10000
integer
1000000
integer
10000
string
random
number
0.8
integer
-1
number
0.2
integer
1
boolean
true
boolean
true
number
3.4
boolean
true
boolean
true
boolean
string
None
boolean
boolean
string
single
integer
100
boolean
boolean
integer
1
boolean
number
1e-15
string
s3://ngi-igenomes/igenomes/
integer
3
number
0.75
string
c(0, 0.7)
number
0.6
integer
20000
string
TRUE
Email address for completion summary.
boolean
Email address for completion summary, only when pipeline fails.
boolean
boolean
Do not use coloured log outputs.
boolean
Send plain-text email instead of HTML.
boolean
Git commit id for Institutional configs.
string
master
Base directory for Institutional configs.
string
https://raw.githubusercontent.com/nf-core/configs/master
Institutional config description.
boolean
Institutional config contact information.
boolean
Institutional config URL link.
boolean
Maximum amount of memory that can be requested for any single job.
string
128 GB
Maximum number of CPUs that can be requested for any single job.
integer
16
Maximum amount of time that can be requested for any single job.
string
10d